| ncRNA name | hsa-miR-518d-3p |
| ncRNA Category | miRNA |
| Disease name | age-related macular degeneration (AMD) |
| Species | Homo sapiens |
| Tissues/Cell_line | human RPE cell line ARPE-19 |
| Methods | MTT assay, ELISA, qRT-PCR |
| Expression pattern | up-regulated |
| Functional description | Expressions of 90 miRNA were significantly changed in the ARPE-19 cells incubated with H2O2 compared to control group. While 24 miRNA upregulated due to the increased dose of H2O2, nine miRNA were also found to be downregulated. These miRNAs may have a role in the pathogenesis of age-related macular degeneration related to oxidative stress. |
| PubMed ID | 28707489 |
| Year | 2018 |
| Title | Evaluation of microRNA responses in ARPE-19 cells against the oxidative stress. |
| Drug-related ncRNA | NO |
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